A new study suggests that about two-thirds of all US coronavirus cases identified in the last three months may be associated with the first variant identified in the United Kingdom.
According to the Centers for Disease Control and Prevention (CDC), there are at least 11,569 cases of this strain known as B1.1.7 in the United States.
However, researchers believe that the actual numbers could be much higher, with 67% of the samples returning positive for the mutation between December 2020 and February 2021. I found that.
Due to its high contagiousness, infection of variants in the United States doubles approximately every 9 days and appears to spread 40 to 50 percent faster than previous variants.
A team led by the Scripps Research Institute states that the findings provide evidence that B.1.1.7 may currently be a major variant of the country.
In the United States, there are at least 11,569 cases of this strain known as B 1.1.7, and cases have been confirmed in all states of the United States.
However, a new study found that between December 2020 and February 2021, 67% of the sequenced samples returned positive for the variant.
Due to its high contagiousness, infection of variants in the United States doubles approximately every 9 days and appears to spread 40-50% faster than previous variants.
“B.1.1.7 has rapidly become a major SARS-CoV-2 variant in the United Kingdom and other countries since its emergence at the end of last year, and the United States is on a similar trajectory,” said the research co-owner. The author, Dr. Christian Andersen, said. Professor of Immunology and Microbiology at Scripps Research.
“Prompt and decisive action is required to minimize the morbidity and mortality of COVID-19.”
The British variant was first discovered in Kent County in September, but was not considered a “Variant of Concern” (VOC) until December.
Its name, B.1.1.7, comes from the location of its most important mutation.
It currently accounts for at least 90 percent of all UK cases.
Most estimates are about 70% more infectious than older “wild-type” coronavirus variants, but milder predictions are only about 56% more contagious.
This is because one of the many mutations in the variant is against the speplomer that the virus uses to invade and infect human cells.
A standard test for coronavirus searches for characteristic gene sequences at three sites, but due to a mutation in the B.1.1.7 variant, only two return positive.
In the first part of the analysis published in the journal Cell, the team looked for this pattern, called S-gene targeting disorder, in 500,000 samples of the virus tested at the Helix facility since July 2020.
From the week of October 18, only 0.2% of daily positive cases appeared to be associated with British variants.
This slowly increased from 0.8% in the first week of January to 10.6% in the third week of February.
In the second part of the analysis, researchers sequenced all SGTF samples from December 2020 to February 2021.
Cases involving new variants are most common in Florida (upper graph) and California (lower graph), doubling every 8.7 and 6.9 days, respectively.
CDC Director Dr. Rochelle Warrensky revealed on Wednesday that B.1.1.7 accounts for 4% to 35% of coronavirus cases, depending on the region.
Of the 986 samples, 662 (67 percent) contained the B.1.1.7 variant.
Researchers have found that most of the B.1.1.7 sequences from the US cluster are in the three states of Florida, California, and Georgia.
The new report estimates that cases double every 6.9 days in California, every 8.7 days in Florida, and every 9.2 days in Georgia.
Michigan officials say the recent surge in cases seen in the state is likely due to mutations.
“The doubling rate for B.1.1.7 is just over a week and the infection rate has increased by 40-50%, which means it can have a significant impact on public health,” Lee said. Mr. says.
“It is important to keep an eye on the spread of this and other new variants, but the current level of surveillance is inadequate and lags behind the level of surveillance in other countries. To address this. Need a more comprehensive national SARS-CoV-2 genomics monitoring program.
At a press conference on Wednesday, CDC director Dr. Rochelle Walensky revealed that B.1.1.7 accounts for 4% to 35% of coronavirus cases, depending on the region.
She states that the CDC believes that this variant now accounts for 26 percent of cases nationwide.
“We are watching this very carefully, but it is starting to become the predominant variant in many US regions,” Warensky said.
“We are starting to see it creep in. We know that it is more contagious and 50% to 70% more contagious than wild-type strains, so people practice standard mitigation strategies. Unless you have, we believe that B.1.1.7 will increase the number of infections. ”
A study found that 67% of cases between December and February were associated with British variants.
Source link A study found that 67% of cases between December and February were associated with British variants.